If you’re looking for the best toothbrush for you, it can be difficult to tell which one will work best. It’s important to find a toothbrush that feels comfortable and works well. Guidelines from the American Dental Association: Powered toothbrushes don’t clean teeth any better than regular toothbrushes. Any toothbrush you choose should have soft bristles. Hard bristles may cause gum tissue to pull back from teeth, which can expose the tooth root and lead to increased sensitivity to heat, cold, or certain foods and drinks.